产品名称
RHG44 Rabbit Polyclonal Antibody
基因名称
ARHGAP44 KIAA0672 RICH2
蛋白名称
Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q17R89
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q17R89/entry
Mouse Swissprot No.
Q5SSM3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5SSM3
免疫原
Synthesized peptide derived from human protein . at AA range: 430-510
特异性
RHG44 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.,
组织表达
Highly expressed in brain. Expressed at weak level in other tissues.
细胞定位
Cell projection, dendritic spine . Recycling endosome . Cell junction, synapse, presynapse . Cell projection, dendrite . In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity). Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (By similarity). .
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
