产品名称
MED19 Rabbit Polyclonal Antibody
蛋白名称
Mediator of RNA polymerase II transcription subunit 19 (Lung cancer metastasis-related protein 1) (Mediator complex subunit 19)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219541
Human Swissprot No.
A0JLT2
Human Swissprot Link
https://www.uniprot.org/uniprot/A0JLT2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=381379
Mouse Swissprot No.
Q8C1S0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C1S0/entry
特异性
This antibody detects endogenous levels of MED19 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
