产品名称
PPIH Rabbit Polyclonal Antibody
蛋白名称
Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10465
Human Swissprot No.
O43447
Human Swissprot Link
https://www.uniprot.org/uniprot/O43447
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66101
Mouse Swissprot No.
Q9D868
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D868/entry
特异性
This antibody detects endogenous levels of PPIH at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus speckle . Cytoplasm . Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
功能
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding . Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.
