产品名称
TTC26 Rabbit Polyclonal Antibody
蛋白名称
Tetratricopeptide repeat protein 26 (TPR repeat protein 26)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79989
Human Swissprot No.
A0AVF1
Human Swissprot Link
https://www.uniprot.org/uniprot/A0AVF1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=264134
Mouse Swissprot No.
Q8BS45
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BS45/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=500086
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5U2N8/entry
特异性
This antibody detects endogenous levels of TTC26 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell projection, cilium . Localizes at the base to the ciliary transition zone. .
功能
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.
