产品名称
MIDN Rabbit Polyclonal Antibody
蛋白名称
Midnolin (Midbrain nucleolar protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=90007
Human Swissprot No.
Q504T8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q504T8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59090
Mouse Swissprot No.
Q3TPJ7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3TPJ7/entry
特异性
This antibody detects endogenous levels of MIDN at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus, nucleolus . Nucleus . Cytoplasm, cytosol . Detected in the nucleus and nucleolus with no expression in the cytoplasm (By similarity). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134). .
功能
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4. Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
