产品名称
KLRG1 Rabbit Polyclonal Antibody
基因名称
KLRG1 CLEC15A MAFA MAFAL
蛋白名称
Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10219
Human Swissprot No.
Q96E93
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96E93
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50928
Mouse Swissprot No.
O88713
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88713/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58975
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64335/entry
特异性
This antibody detects endogenous levels of KLRG1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
细胞定位
Cell membrane ; Single-pass type II membrane protein .
功能
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
