产品名称
CPNE6 Rabbit Polyclonal Antibody
蛋白名称
Copine-6 (Copine VI) (Neuronal-copine) (N-copine)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9362
Human Swissprot No.
O95741
Human Swissprot Link
https://www.uniprot.org/uniprot/O95741
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12891
Mouse Swissprot No.
Q9Z140
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z140/entry
特异性
This antibody detects endogenous levels of CPNE6 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed in the brain (PubMed:9645480, PubMed:10403379, PubMed:12949241). Expressed weakly in the kidney, liver and fetal heart (PubMed:12949241). Expressed in melanocytes (PubMed:23999003).
细胞定位
Cytoplasm . Cell membrane . Endosome . Cytoplasmic vesicle, clathrin-coated vesicle . Perikaryon . Cell projection, dendrite . Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner. .
功能
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity). Plays a role in dendrite formation by melanocytes .
