产品名称
LZTS1 Rabbit Polyclonal Antibody
蛋白名称
Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11178
Human Swissprot No.
Q9Y250
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y250
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=211134
Mouse Swissprot No.
P60853
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P60853/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266711
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CFC9/entry
特异性
This antibody detects endogenous levels of LZTS1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in testis, prostate, spleen, thymus, ovary and brain. Detected at lower levels in heart, placenta, small intestine, colon, liver, kidney, skeletal muscle and pancreas. Not detectable in primary tumors from breast and prostate and in many cancer cell lines.
细胞定位
Cytoplasm . Cell membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Associated with the plasma membrane and with microtubules. Detected in dendritic spines, especially in the postsynaptic density (By similarity). .
功能
Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.
