产品名称
NOTUM Rabbit Polyclonal Antibody
蛋白名称
Protein notum homolog (EC 3.-.-.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=147111
Human Swissprot No.
Q6P988
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6P988
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=77583
Mouse Swissprot No.
Q8R116
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R116/entry
特异性
This antibody detects endogenous levels of NOTUM at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Rarely expressed in adult normal tissues.
功能
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors .
