产品名称
RHG25 Rabbit Polyclonal Antibody
蛋白名称
Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P42331
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P42331/entry
Mouse Swissprot No.
Q8BYW1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BYW1
免疫原
Synthesized peptide derived from human protein . at AA range: 370-450
特异性
RHG25 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008],
组织表达
Blood,Bone marrow,Cord blood,Umbilical cord blood,
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.