产品名称
ARHGAP21 Rabbit Polyclonal Antibody
基因名称
ARHGAP21 ARHGAP10 KIAA1424
蛋白名称
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57584
Human Swissprot No.
Q5T5U3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5T5U3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71435
Mouse Swissprot No.
Q6DFV3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6DFV3/entry
特异性
This antibody detects endogenous levels of ARHGAP21 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed with higher expression in brain, heart, skeletal muscle and placenta.
细胞定位
Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
功能
Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
