产品名称
SUNC1 Rabbit Polyclonal Antibody
蛋白名称
SUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=256979
Human Swissprot No.
Q8TAQ9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TAQ9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=194974
Mouse Swissprot No.
Q5SS91
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5SS91/entry
特异性
This antibody detects endogenous levels of SUNC1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Membrane ; Single-pass membrane protein . Nucleus envelope . Nucleus inner membrane .
功能
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
