产品名称
PHIP Rabbit Polyclonal Antibody
蛋白名称
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55023
Human Swissprot No.
Q8WWQ0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WWQ0
Mouse Swissprot No.
Q8VDD9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VDD9/entry
特异性
This antibody detects endogenous levels of PHIP at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in myeloma and epidermoid carcinoma cell lines.
功能
Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.