产品名称
HSPBP1 Rabbit Polyclonal Antibody
蛋白名称
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23640
Human Swissprot No.
Q9NZL4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NZL4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66245
Mouse Swissprot No.
Q99P31
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99P31/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=246146
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IMX7/entry
特异性
This antibody detects endogenous levels of HSPBP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
