产品名称
SLIRP Rabbit Polyclonal Antibody
基因名称
SLIRP C14orf156 DC23 DC50 PD04872
蛋白名称
SRA stem-loop-interacting RNA-binding protein, mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81892
Human Swissprot No.
Q9GZT3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9GZT3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=380773
Mouse Swissprot No.
Q9D8T7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D8T7/entry
特异性
This antibody detects endogenous levels of SLIRP at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.
细胞定位
Mitochondrion . Nucleus . Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
功能
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
