产品名称
TIG3 Rabbit Polyclonal Antibody
蛋白名称
Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UL19
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UL19/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
TIG3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Single-pass membrane protein .
功能
function:May be a growth regulator that mediates some of the growth suppressive effects of retinoids.,induction:By tazarotene.,similarity:Belongs to the H-rev107 family.,tissue specificity:Expressed in many tissues. Not expressed in heart, brain, and testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
