产品名称
C7orf47 Rabbit Polyclonal Antibody
蛋白名称
Protein phosphatase 1 regulatory subunit 35
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=221908
Human Swissprot No.
Q8TAP8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TAP8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69871
Mouse Swissprot No.
Q9D8C8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D8C8/entry
特异性
This antibody detects endogenous levels of C7orf47 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel (PubMed:30168418, PubMed:30230954). Co-localizes with RTTN at the centriole (PubMed:30168418). .
功能
During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion . In addition, may play a role in the primary cilia assembly (By similarity).
