产品名称
RHBDF2 Rabbit Polyclonal Antibody
基因名称
RHBDF2 IRHOM2 RHBDL5 RHBDL6
蛋白名称
Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79651
Human Swissprot No.
Q6PJF5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6PJF5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=217344
Mouse Swissprot No.
Q80WQ6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80WQ6/entry
特异性
This antibody detects endogenous levels of RHBDF2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Found in the epidermis and esophageal epithelium.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane .
功能
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.