产品名称
TRIAP1 Rabbit Polyclonal Antibody
基因名称
TRIAP1 15E1.1 HSPC132
蛋白名称
TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51499
Human Swissprot No.
O43715
Human Swissprot Link
https://www.uniprot.org/uniprot/O43715
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69076
Mouse Swissprot No.
Q9D8Z2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D8Z2/entry
特异性
This antibody detects endogenous levels of TRIAP1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion . Mitochondrion intermembrane space .
功能
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane . Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) . Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis .
