产品名称
IER2 Rabbit Polyclonal Antibody
蛋白名称
Immediate early response gene 2 protein (Protein ETR101)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9592
Human Swissprot No.
Q9BTL4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BTL4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15936
Mouse Swissprot No.
P17950
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P17950/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=494344
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P7D3/entry
特异性
This antibody detects endogenous levels of IER2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in activated T-cells (at protein level) (PubMed:22120713). Expression increases in metastatic tumor cells (at protein level) (PubMed:22120713).
细胞定位
Cytoplasm . Nucleus . Cytoplasmic during quiescence, translocates to the nucleus upon stimulation. .
功能
DNA-binding protein that seems to act as a transcription factor . Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis .
