产品名称
SEPX1 Rabbit Polyclonal Antibody
蛋白名称
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51734
Human Swissprot No.
Q9NZV6
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NZV6
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27361
Mouse Swissprot No.
Q9JLC3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JLC3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=685059
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q52KJ8/entry
特异性
This antibody detects endogenous levels of SEPX1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton .
功能
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.
