产品名称
RGS21 Rabbit Polyclonal Antibody
蛋白名称
Regulator of G-protein signaling 21 (RGS21)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q2M5E4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2M5E4/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
RGS21 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008],
组织表达
Expressed ubiquitously.
细胞定位
cytoplasm,plasma membrane,
功能
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 1 RGS domain.,tissue specificity:Expressed ubiquitously.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
