产品名称
SNIP1 Rabbit Polyclonal Antibody
蛋白名称
Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79753
Human Swissprot No.
Q8TAD8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TAD8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76793
Mouse Swissprot No.
Q8BIZ6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BIZ6/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100912429
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5M9G6/entry
特异性
This antibody detects endogenous levels of SNIP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous, with highest expression in heart and skeletal muscle.
功能
Required for pre-mRNA splicing as component of the spliceosome . Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
