产品名称
NIP30 Rabbit Polyclonal Antibody
基因名称
FAM192A C16orf94 NIP30 CDA018 CDA10
蛋白名称
Protein FAM192A (NEFA-interacting nuclear protein NIP30)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80011
Human Swissprot No.
Q9GZU8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9GZU8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=102122
Mouse Swissprot No.
Q91WE2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91WE2/entry
特异性
This antibody detects endogenous levels of NIP30 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.
