产品名称
TASP1 Rabbit Polyclonal Antibody
蛋白名称
Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55617
Human Swissprot No.
Q9H6P5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H6P5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75812
Mouse Swissprot No.
Q8R1G1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1G1/entry
特异性
This antibody detects endogenous levels of TASP1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Protease responsible for KMT2A/MLL1 processing and activation . It also activates KMT2D/MLL2 (By similarity). Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A (By similarity) .
