产品名称
COX20 Rabbit Polyclonal Antibody
蛋白名称
Cytochrome c oxidase protein 20 homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116228
Human Swissprot No.
Q5RI15
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5RI15
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66359
Mouse Swissprot No.
Q9D7J4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D7J4/entry
特异性
This antibody detects endogenous levels of COX20 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase . Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme .