产品名称
EIF2C1 Rabbit Polyclonal Antibody
蛋白名称
Protein argonaute-1 (Argonaute1) (hAgo1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26523
Human Swissprot No.
Q9UL18
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UL18
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=236511
Mouse Swissprot No.
Q8CJG1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CJG1/entry
特异性
This antibody detects endogenous levels of EIF2C1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
