产品名称
SEC11A Rabbit Polyclonal Antibody
基因名称
SEC11A SEC11L1 SPC18 SPCS4A
蛋白名称
Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23478
Human Swissprot No.
P67812
Human Swissprot Link
https://www.uniprot.org/uniprot/P67812
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56529
Mouse Swissprot No.
Q9R0P6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R0P6/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P42667/entry
特异性
This antibody detects endogenous levels of SEC11A at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
功能
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum . Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids .
