产品名称
Syntabulin Rabbit Polyclonal Antibody
基因名称
SYBU GOLSYN KIAA1472
蛋白名称
Syntabulin (Golgi-localized syntaphilin-related protein) (Syntaxin-1-binding protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55638
Human Swissprot No.
Q9NX95
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NX95
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=319613
Mouse Swissprot No.
Q8BHS8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHS8/entry
特异性
This antibody detects endogenous levels of Syntabulin at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine.
细胞定位
[Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Colocalizes with syntaxin vesicles along microtubules in neuronal processes.; [Isoform 3]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 4]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 5]: Golgi apparatus membrane; Single-pass membrane protein.
功能
Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.