产品名称
GPD1L Rabbit Polyclonal Antibody
蛋白名称
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1-L) (EC 1.1.1.8)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23171
Human Swissprot No.
Q8N335
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N335
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=333433
Mouse Swissprot No.
Q3ULJ0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3ULJ0/entry
特异性
This antibody detects endogenous levels of GPD1L at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs.
细胞定位
Cytoplasm . Localized to the region of the plasma membrane.
功能
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
