产品名称
JAKMIP1 Rabbit Polyclonal Antibody
基因名称
JAKMIP1 GABABRBP JAMIP1 MARLIN1
蛋白名称
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=152789
Human Swissprot No.
Q96N16
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96N16
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76071
Mouse Swissprot No.
Q8BVL9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BVL9/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=305434
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q3SWS9/entry
特异性
This antibody detects endogenous levels of JAKMIP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
细胞定位
Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
功能
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
