产品名称
AIDA Rabbit Polyclonal Antibody
蛋白名称
Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64853
Human Swissprot No.
Q96BJ3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96BJ3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108909
Mouse Swissprot No.
Q8C4Q6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C4Q6/entry
特异性
This antibody detects endogenous levels of AIDA at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
功能
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
