产品名称
LZTFL1 Rabbit Polyclonal Antibody
蛋白名称
Leucine zipper transcription factor-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54585
Human Swissprot No.
Q9NQ48
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NQ48
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93730
Mouse Swissprot No.
Q9JHQ5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHQ5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=316102
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q562C6/entry
特异性
This antibody detects endogenous levels of LZTFL1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes.
功能
Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.