产品名称
Galectin 10 Rabbit Polyclonal Antibody
蛋白名称
Eosinophil lysophospholipase (EC 3.1.1.5) (Charcot-Leyden crystal protein) (CLC) (Galectin-10) (Gal-10) (Lysolecithin acylhydrolase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1178
Human Swissprot No.
Q05315
Human Swissprot Link
https://www.uniprot.org/uniprot/Q05315
Mouse Swissprot No.
P97400
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P97400/entry
特异性
This antibody detects endogenous levels of Galectin 10 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).
细胞定位
Cytoplasm, cytosol . Cytoplasmic granule . Localized in granules from where it may be secreted or transported to other locations in the cell.
功能
Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
