产品名称
PRMT8 Rabbit Polyclonal Antibody
基因名称
PRMT8 HRMT1L3 HRMT1L4
蛋白名称
Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56341
Human Swissprot No.
Q9NR22
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NR22
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=381813
Mouse Swissprot No.
Q6PAK3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PAK3/entry
特异性
This antibody detects endogenous levels of PRMT8 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
功能
S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer . Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS .
