产品名称
RAB8B Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-8B
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92930
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92930/entry
Mouse Swissprot No.
P61028
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P61028
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P70550
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
RAB8B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010],
组织表达
Fetal brain,Lung,Melanoma,
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus or M.tuberculosis.
功能
function:May be involved in vesicular trafficking and neurotransmitter release.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with OTOF and PEX5R.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
