产品名称
C4BPA Rabbit Polyclonal Antibody
蛋白名称
C4b-binding protein alpha chain (C4bp) (Proline-rich protein) (PRP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=722
Human Swissprot No.
P04003
Human Swissprot Link
https://www.uniprot.org/uniprot/P04003
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12269
Mouse Swissprot No.
P08607
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P08607/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63514/entry
特异性
This antibody detects endogenous levels of C4BPA at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Chylomicrons in the plasma.
功能
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
