产品名称
PBRM1 Rabbit Polyclonal Antibody
蛋白名称
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55193
Human Swissprot No.
Q86U86
Human Swissprot Link
https://www.uniprot.org/uniprot/Q86U86
Mouse Swissprot No.
Q8BSQ9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BSQ9/entry
特异性
This antibody detects endogenous levels of PBRM1 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.
