产品名称
PPP1R12B Rabbit Polyclonal Antibody
蛋白名称
Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4660
Human Swissprot No.
O60237
Human Swissprot Link
https://www.uniprot.org/uniprot/O60237
Mouse Swissprot No.
Q8BG95
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BG95/entry
特异性
This antibody detects endogenous levels of PPP1R12B at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific.
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, stress fiber . Along actomyosin filaments. .
功能
Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
