产品名称
ACOT7 Rabbit Polyclonal Antibody
蛋白名称
Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11332
Human Swissprot No.
O00154
Human Swissprot Link
https://www.uniprot.org/uniprot/O00154
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70025
Mouse Swissprot No.
Q91V12
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91V12/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26759
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64559/entry
特异性
This antibody detects endogenous levels of ACOT7 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform 4 is expressed exclusively in brain.
细胞定位
[Isoform 4]: Cytoplasm, cytosol .; [Isoform 6]: Cytoplasm, cytosol .; [Isoform 1]: Mitochondrion .; [Isoform 5]: Mitochondrion .
功能
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels . Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18 . May play an important physiological function in brain .
