产品名称
ASIC2 Rabbit Polyclonal Antibody
基因名称
ASIC2 ACCN ACCN1 BNAC1 MDEG
蛋白名称
Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=40
Human Swissprot No.
Q16515
Human Swissprot Link
https://www.uniprot.org/uniprot/Q16515
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11418
Mouse Swissprot No.
Q925H0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q925H0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25364
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q62962/entry
特异性
This antibody detects endogenous levels of ASIC2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
细胞定位
Cell membrane ; Multi-pass membrane protein . Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. .
功能
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
