产品名称
RB40L Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-40A-like (Ras-like GTPase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P0C0E4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P0C0E4/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 90-170
特异性
RB40L Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy. [provided by RefSeq, Apr 2010],
组织表达
Expressed in brain, lung, heart, skeletal muscle, kidney and liver. Highest expression in brain. Expressed in fetal brain and kidney.
细胞定位
Membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Mitochondrion .
功能
domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,tissue specificity:Expressed in brain, heart, skeletal muscle, kidney and liver. Highest expression in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
