产品名称
CC2D2A Rabbit Polyclonal Antibody
蛋白名称
Coiled-coil and C2 domain-containing protein 2A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57545
Human Swissprot No.
Q9P2K1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9P2K1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231214
Mouse Swissprot No.
Q8CFW7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CFW7/entry
特异性
This antibody detects endogenous levels of CC2D2A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart.
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. .
功能
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
