产品名称
EPSTI1 Rabbit Polyclonal Antibody
蛋白名称
Epithelial-stromal interaction protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94240
Human Swissprot No.
Q96J88
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96J88
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108670
Mouse Swissprot No.
Q8VDI1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VDI1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=498547
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5BK43/entry
特异性
This antibody detects endogenous levels of EPSTI1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE).
功能
Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity).
