产品名称
LRRC17 Rabbit Polyclonal Antibody
基因名称
LRRC17 P37NB UNQ3076/PRO9909
蛋白名称
Leucine-rich repeat-containing protein 17 (p37NB)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10234
Human Swissprot No.
Q8N6Y2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N6Y2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74511
Mouse Swissprot No.
Q9CXD9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CXD9/entry
特异性
This antibody detects endogenous levels of LRRC17 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells.
细胞定位
Secreted, extracellular space .
功能
Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity).
