产品名称
INTS5 Rabbit Polyclonal Antibody
蛋白名称
Integrator complex subunit 5 (Int5)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80789
Human Swissprot No.
Q6P9B9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6P9B9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109077
Mouse Swissprot No.
Q8CHT3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CHT3/entry
特异性
This antibody detects endogenous levels of INTS5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus membrane ; Multi-pass membrane protein . Nucleus . Cytoplasm .
功能
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex .
