产品名称
FMNL1 Rabbit Polyclonal Antibody
基因名称
FMNL1 C17orf1 C17orf1B FMNL
蛋白名称
Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=752
Human Swissprot No.
O95466
Human Swissprot Link
https://www.uniprot.org/uniprot/O95466
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57778
Mouse Swissprot No.
Q9JL26
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JL26/entry
特异性
This antibody detects endogenous levels of FMNL1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
细胞定位
Cytoplasm . Cell membrane ; Lipid-anchor . Cytoplasmic vesicle, phagosome . Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1 (By similarity). .; [Isoform 3]: Cytoplasm, cell cortex. Cell projection, bleb. Colocalized with F-actin in bleb protrusions.
功能
May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
