产品名称
SCYL2 Rabbit Polyclonal Antibody
基因名称
SCYL2 CVAK104 KIAA1360
蛋白名称
SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55681
Human Swissprot No.
Q6P3W7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6P3W7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=213326
Mouse Swissprot No.
Q8CFE4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CFE4/entry
特异性
This antibody detects endogenous levels of SCYL2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasmic vesicle, clathrin-coated vesicle . Golgi apparatus, trans-Golgi network membrane . Endosome membrane . Colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes. .
功能
Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system (Probable). A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed . By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (By similarity).
