产品名称
CPLX3 Rabbit Polyclonal Antibody
蛋白名称
Complexin-3 (Complexin III) (CPX III)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=594855
Human Swissprot No.
Q8WVH0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WVH0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=235415
Mouse Swissprot No.
Q8R1B5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1B5/entry
特异性
This antibody detects endogenous levels of CPLX3 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell junction, synapse . Cell membrane; Lipid-anchor . Enriched at the synaptic terminal (By similarity). Localized at glycinergic synaptic contacts of AII amacrine cells with OFF cone bipolar cells in the OFF sublamina of the retina inner nuclear layer (By similarity). .
功能
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity).
