产品名称
RAB8B Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-8B
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92930
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92930/entry
Mouse Swissprot No.
P61028
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P61028
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P70550
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
RAB8B Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010],
组织表达
Fetal brain,Lung,Melanoma,
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus or M.tuberculosis.
功能
function:May be involved in vesicular trafficking and neurotransmitter release.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with OTOF and PEX5R.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
